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UK Drugs in Lactation Advisory Service

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Antidiarrhoeals

Drugs
Suitability for use in lactation
Comments

* First line treatment of acute diarrhoea is appropriate fluid and electrolyte replacement. This table only considers second-line symptomatic treatment.

* Drugs for chronic diarrhoea, e.g. associated with inflammatory bowel disease, irritable bowel syndrome etc. are not included.

Adsorbents Kaolin Yes

Not absorbed from gatrointestinal tract.
Not routinely recommended for acute diarrhoea.

Antimotility agents Codeine phosphate Yes Only small amounts in breast milk.
Considered safe for short-term use
  Co-phenotrope
Diphenoxylate + atropine
(Lomotil)
? No specific data.
Prefer use of other agents.
  Loperamide Yes Only small amounts in breast milk.
Considered safe for short-term use

Drugs classified with '?' should be used with caution and only after an assessment of benefit to the mother versus risk, real or potential, to the infant. These drugs either have insufficient clinical data on their use in lactation to regard as absolutely safe or they have had minor, reversible side effects reported in a breast-fed infant.