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UK
Drugs in Lactation Advisory Service
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Anticoagulants
- Individual
maternal and infant situations must be taken into account before any
drug is prescribed for the mother.
- In
general, all drugs should be avoided in premature or low birth weight
infants, or in those who have any underlying conditions.
- If
a drug is prescribed, it should be at the lowest practical dose and
for the shortest time.
|
Drugs
|
Suitability
for use in lactation
|
Comments
|
|
|
| Oral
anticoagulants |
Warfarin |
Yes |
Oral
anticoagulant of choice during breast feeding. Very low levels in
milk. No effects on infant. |
| Phenindione |
No |
Single
report of haematoma in breast-fed infant |
| Heparins |
Heparin
sodium/calcium |
Yes |
|
| Low
molecular weight heparins |
Yes |
Not
absorbed by infant but limited clinical experience |
Drugs
classified with '?' should be used with caution and only after an assessment
of benefit to the mother versus risk, real or potential, to the infant.
These drugs either have insufficient clinical data on their use in lactation
to regard as absolutely safe or they have had minor, reversible side effects
reported in a breast-fed infant.
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